Oleoylethanolamide (OEA) is a naturally occurring ethanolamide lipid derived from oleic acid. It acts as an endogenous peroxisome proliferator-activated receptor alpha (PPAR-α) agonist, playing a role in lipid signaling pathways and enzymatic regulation.
OEA is synthesized via N-acylphosphatidylethanolamine hydrolysis, with degradation occurring through fatty acid amide hydrolase (FAAH) activity.
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